Dr. Tao Hong
Principal Investigator
Professor of Neurosurgery, M.D.
Vice President, Xuanwu Hospital Capital Medical University
Professor of Neurosurgery, M.D.
Vice President, Xuanwu Hospital Capital Medical University
Dr. Hong leads translational research in human vascular diseases of the brain and spinal cord, seamlessly integrating fundamental science, clinical practice, and therapeutic development.
Google Scholar | [CV]
Google Scholar | [CV]
OUR TEAM
Research Scientists
Dr. Ye Li
Associate Professor, M.D.
Department of Neurosurgery
Department of Neurosurgery
Intracerebral Hemorrhage
Dr. Ye Li
Dr. Li focuses on clinical and medical-engineering interdisciplinary research in intracerebral hemorrhage, leading clinical trials to develop strategies for mitigating hemorrhagic brain injury and optimizing patient prognosis.
Funding:
Noncommunicable Chronic Diseases-National Science and Technology Major Project
Featured:
Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort study. [The Lancet Regional Health - Western Pacific]
Funding:
Noncommunicable Chronic Diseases-National Science and Technology Major Project
Featured:
Short-term surgical outcomes of spontaneous intracerebral hemorrhage in China from 2019 to 2021: a retrospective cohort study. [The Lancet Regional Health - Western Pacific]
Dr. Jiaxing Yu
Associate Professor, M.D.
Department of Neurosurgery
Department of Neurosurgery
Arteriovenous Malformation
Dr. Jiaxing Yu
Dr. Yu investigates the molecular mechanisms of brain and spinal arteriovenous malformations (AVMs) and drives the development of novel therapeutic agents.
Funding:
National Natural Science Foundation of China (General Programs)
Featured:
Inhibition of Angiopoietin-2 rescues sporadic brain arteriovenous malformations by reducing pericyte loss. [Angiogenesis]
Funding:
National Natural Science Foundation of China (General Programs)
Featured:
Inhibition of Angiopoietin-2 rescues sporadic brain arteriovenous malformations by reducing pericyte loss. [Angiogenesis]
Dr. Jian Ren
Associate Professor, M.D.
Department of Neurosurgery
Department of Neurosurgery
Cavernous Malformation
Dr. Jian Ren
Dr. Ren investigates the genetic mechanisms, key signaling pathways, and targeted therapies of central nervous system cavernous malformations (CNS-CMs).
Funding:
National Natural Science Foundation of China (General & Young Investigator Programs)
Featured:
Angiogenic switching in cerebral cavernous malformations driven by MAP3K3-PIK3CA synergy. [Brain]
Funding:
National Natural Science Foundation of China (General & Young Investigator Programs)
Featured:
Angiogenic switching in cerebral cavernous malformations driven by MAP3K3-PIK3CA synergy. [Brain]
Dr. Chendan Jiang
Attending Neurosurgeon, M.D.
Department of Neurosurgery
Department of Neurosurgery
Bioinformatics
Dr. Chendan Jiang
Dr. Jiang applies bioinformatic approaches to identify novel etiological factors and therapeutic targets for vascular diseases of the brain and spinal cord.
Featured:
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations. [Angiogenesis]
GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas. [American Journal of Human Genetics]
Featured:
Somatic BrafV600E mutation in the cerebral endothelium induces brain arteriovenous malformations. [Angiogenesis]
GNA14 and GNAQ somatic mutations cause spinal and intracranial extra-axial cavernous hemangiomas. [American Journal of Human Genetics]
Dr. Shikun Zhang
Research Fellow, Ph.D.
Department of Neurosurgery
Department of Neurosurgery
Intracerebral Hemorrhage
Dr. Shikun Zhang
Dr. Zhang focuses on basic research of intracerebral hemorrhage. His work specializes in elucidating the complex cross-talk between post-hemorrhage injury and immune responses.
Funding:
Noncommunicable Chronic Diseases-National Science and Technology Major Project
Featured:
Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response. [Cell]
Funding:
Noncommunicable Chronic Diseases-National Science and Technology Major Project
Featured:
Self-Recognition of an Inducible Host lncRNA by RIG-I Feedback Restricts Innate Immune Response. [Cell]
Dr. Jingjing Wang
Attending Neurosurgeon, M.D.
Department of Neurosurgery
Department of Neurosurgery
Interventional Device R&D
Dr. Jingjing Wang
Dr. Wang focuses on material science, driving the research and development of biocompatible neurointerventional devices.
Funding:
National Natural Science Foundation of China Young Scientists Fund
Featured:
Critical biomarkers for responsive deep brain stimulation and responsive focal cortex stimulation in epilepsy field. [Fundamental Research]
Funding:
National Natural Science Foundation of China Young Scientists Fund
Featured:
Critical biomarkers for responsive deep brain stimulation and responsive focal cortex stimulation in epilepsy field. [Fundamental Research]
Dr. Zhuofan Xu
Attending Neurosurgeon, M.D.
Department of Neurosurgery
Department of Neurosurgery
Organoids and Stem Cells
Dr. Zhuofan Xu
Dr. Xu is constructing brain organoid and stem cell models. Her work will provide novel platforms for neurovascular research.
Featured:
Toward a molecular era in brain arteriovenous malformation management. [Journal of Neurointerventional Surgery]
Interleukin-7 expression by CAR-T cells improves CAR-T cell survival and efficacy in chordoma. [Cancer Immunology, Immunotherapy]
Featured:
Toward a molecular era in brain arteriovenous malformation management. [Journal of Neurointerventional Surgery]
Interleukin-7 expression by CAR-T cells improves CAR-T cell survival and efficacy in chordoma. [Cancer Immunology, Immunotherapy]
Dr. Yeqing Ren
Neurosurgery Resident, M.D.
Department of Neurosurgery
Department of Neurosurgery
Cavernous Malformation
Gamma Knife Radiosurgery
Gamma Knife Radiosurgery
Dr. Yeqing Ren
Dr. Ren investigates cerebral and spinal cavernous malformations (CMs), translating pathogenic insights to further explore and optimize Gamma Knife and precision radiosurgery applications.
Featured:
Angiogenic switching in cerebral cavernous malformations driven by MAP3K3-PIK3CA synergy. [Brain]
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations. [Brain]
Featured:
Angiogenic switching in cerebral cavernous malformations driven by MAP3K3-PIK3CA synergy. [Brain]
Somatic variants of MAP3K3 are sufficient to cause cerebral and spinal cord cavernous malformations. [Brain]
Dr. Shaohua Mo
Neurosurgery Resident, M.D.
Department of Neurosurgery
Department of Neurosurgery
Intracerebral Hemorrhage
Dr. Shaohua Mo
Dr. Mo leads clinical trials on intracerebral hemorrhage to expand diversified therapeutic strategies.
Featured:
Safety and efficacy of early versus delayed acetylsalicylic acid after surgery for spontaneous intracerebral haemorrhage in China (E-start): a prospective, multicentre, open-label, blinded-endpoint, randomised trial. [The Lancet. Neurology]
A decision tree model to help treatment decision-making for severe spontaneous intracerebral hemorrhage. [International Journal of Surgery]
Featured:
Safety and efficacy of early versus delayed acetylsalicylic acid after surgery for spontaneous intracerebral haemorrhage in China (E-start): a prospective, multicentre, open-label, blinded-endpoint, randomised trial. [The Lancet. Neurology]
A decision tree model to help treatment decision-making for severe spontaneous intracerebral hemorrhage. [International Journal of Surgery]
Post-Doctoral Researchers
Dr. Lingui Gu
Postdoctoral Research Fellow, M.D.
Department of Neurosurgery
Department of Neurosurgery
Intracerebral Hemorrhage
Dr. Lingui Gu
Dr. Gu specializes in using single-cell and spatial transcriptomics approaches to explore secondary neurological damage following intracerebral hemorrhage.
Funding:
Special Research Fund for Central Universities, Peking Union Medical College
Featured:
Unraveling dynamic immunological landscapes in intracerebral hemorrhage: insights from single-cell and spatial transcriptomic profiling. [Medcomm]
Funding:
Special Research Fund for Central Universities, Peking Union Medical College
Featured:
Unraveling dynamic immunological landscapes in intracerebral hemorrhage: insights from single-cell and spatial transcriptomic profiling. [Medcomm]
Graduate Students
Ziwei Cui
2024-2027
M.D. Student
M.D. Student
Organoids and Stem Cells
Chi Ma
2024-2027
M.D. Student
M.D. Student
Intracerebral Hemorrhage
Anxiang Dai
2024-2027
M.D. Student
M.D. Student
Arteriovenous Malformation
Haohan Lu
2025-2028
M.D. Student
M.D. Student
Intracerebral Hemorrhage
Yafan Liu
2025-2028
M.D. Student
M.D. Student
Cavernous Malformation
Ke Wang
2025-2028
Ph.D. Student
Ph.D. Student
Organoids and Stem Cells
Yiying Mai
2025-2028
M.D. Student
M.D. Student
Organoids and Stem Cells
Jinxin Lan
2025-2028
M.D. Student
M.D. Student
Arteriovenous Malformation
Ruoru Wu
2026-2029
M.D. Student
M.D. Student
Intracerebral Hemorrhage
Daochao Wang
2026-2029
M.D. Student
M.D. Student
Cavernous Malformation
Xiaosheng Meng
2026-2029
M.D. Student
M.D. Student
Arteriovenous Malformation
Guangyao Shi
2026-2029
M.D. Student
M.D. Student
Intracerebral Hemorrhage
Yubo Liu
2022-2032
Ph.D. Student
Ph.D. Student
Cavernous Malformation
Chunyu Zhang
2023-2033
Ph.D. Student
Ph.D. Student
Intracerebral Hemorrhage
Menghao Zhang
2024-2027
M.Med. Student
M.Med. Student
Arteriovenous Malformation
Hao Yu
2024-2027
M.Med. Student
M.Med. Student
Cavernous Malformation
Ziyang Zhang
2024-2027
M.Med. Student
M.Med. Student
Intracerebral Hemorrhage
Chenghao Pan
2025-2028
M.Med. Student
M.Med. Student
Bioinformatics
Yibo Wang
2025-2028
M.Med. Student
M.Med. Student
Arteriovenous Malformation
Yuxin Xie
2025-2028
M.Sc. Student
M.Sc. Student
Organoids and Stem Cells
Yi Liu
2025-2028
M.Med. Student
M.Med. Student
Cavernous Malformation
Shenhao Chen
2026-2029
M.Med. Student
M.Med. Student
Interventional Device R&D
Runfeng Shi
2026-2029
M.Med. Student
M.Med. Student
Intracerebral Hemorrhage
Staff
Jiawen Liu
Technician
Research Assistant
Undergraduate Students
Ningxin Lu
Undergraduate Student
Cavernous Malformation
Alumni
Dr. Tianqi Tu
2021-2024
Postdoctoral, Dept. of Neurosurgery
The Affiliated Hospital of Southwest Medical University
Postdoctoral, Dept. of Neurosurgery
The Affiliated Hospital of Southwest Medical University
Dr. Zhengsong Li
2021-2024
Resident, Dept. of Neurosurgery
Hu'nan Provincial People's Hospital, Hunan University
Resident, Dept. of Neurosurgery
Hu'nan Provincial People's Hospital, Hunan University
M.Med. Yuan Zhou
2021-2024
Resident, Dept. of Anesthesiology
Xuanwu Hospital, Capital Medical University
Resident, Dept. of Anesthesiology
Xuanwu Hospital, Capital Medical University
Dr. Shiju Zhang
2020-2026
Postdoctoral, Dept. of Neurosurgery
Fuwai Hospital, Chinese Academy of Medical Sciences
Postdoctoral, Dept. of Neurosurgery
Fuwai Hospital, Chinese Academy of Medical Sciences
Dr. Yueshan Feng
2023-2026
Resident, Dept. of Pain Medicine
Xuanwu Hospital, Capital Medical University
Resident, Dept. of Pain Medicine
Xuanwu Hospital, Capital Medical University
Dr. An Tian
2023-2026
Resident, Dept. of Neurosurgery
Beijing Anzhen Hospital, Capital Medical University
Resident, Dept. of Neurosurgery
Beijing Anzhen Hospital, Capital Medical University
Dr. Hongyun Zhang
2023-2026
Resident, Dept. of Neurosurgery
Henan Provincial People's Hospital, Zhengzhou University
Resident, Dept. of Neurosurgery
Henan Provincial People's Hospital, Zhengzhou University